Scientific Programme
Programme - Thursday 24th of October 2024
Hands-on training on Waters Select Series cIMS with PAL Liquid Handling Robot and HDX-Manager System, Thermo Orbitrap Tribrid Ascend, HDExaminer.
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11:30 – 12:30 |
Conference registration, pizza lunch, divide into groups |
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12:30 – 13:30 |
Glenn Masson: HDX-MS Theory and Practice – Overview of solvent exchange, sample considerations, limitations and controls. |
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13:30-14:00 |
Coffee Break |
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14:00 – 15:00 |
Group 1 Hands-on Training on Waters cIMS, PAL and HDX-Manager System, ECD demonstration
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Group 2 Hand-on Training on Thermo System, P1 peptide fragmentation for HDX-MS/MS. Trajan HDX-Manager demonstration |
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15:00 – 16:00 |
Group 1 Hand-on Training on Thermo System, P1 peptide fragmentation for HDX-MS/MS. Trajan HDX-Manager demonstration |
Group 2 Hands-on Training on Waters cIMS, PAL and HDX-Manager System, ECD demonstration
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16:00-16:15 |
Swift Coffee |
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16:15-17:15
17:30 |
Trajan-Lead HDExaminer Demonstration, Q + A
Informal Networking Event at The George Orwell |
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Programme - Friday 25th October 2024
Our keynote speaker will be Prof. Stephan Rauschenback, University of Oxford, who has pioneered "soft landing" techniques at the interface of mass Spectrometry and cryo-electron microscopy.
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9:00 – 9:45 |
Conference Registration |
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Session 1 |
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9:40 – 9:45 |
Welcome and Introduction to BMS-SIG |
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9:45 – 10:30 |
Keynote Lecture |
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Dr Stephan Rauschenbach, University of Oxford |
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10:30 – 10:45 |
Dr Ikhlas Mohamed Mohamud Ahmed, University of Strathclyde Ion mobility mass spectrometry unveils conformational effects of drug lead EPI-001 on the intrinsically disordered NTD of the Androgen Receptor |
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10:45 – 11:00 |
Dr Rod Chalk, University of Oxford Effect of Entropy upon Electrospray Charge Distribution |
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11:00 – 11:45 |
Coffee Break |
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Session 2 |
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11:45 – 12:00 |
Dr Valeria Calvaresi, University of Oxford A hydrogen-deuterium exchange mass spectrometry (HDX-MS) workflow for residue- and glycan-level analysis of glycoproteins |
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12:00 – 12:15 |
Dr Anna Simmonds, University of Leeds Towards structural mass spectrometry for fragment-based drug discovery |
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12:15 – 12:30 |
Laila Shah, University of Oxford A Bird's-Eye View: Light-Induced Conformational Changes in Avian Cryptochromes |
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12:30 – 12:45 |
Poster flash talks |
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12:45 – 2:00 |
Lunch and Posters |
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Session 3 |
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2:00 – 2:15 |
Dr Anton Calabrese, University of Leeds Development of novel photoactivatable chemical crosslinking reagents |
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2:15 – 2:30 |
Dr Aneika Leney, University of Birmingham Detecting protein complexes directly from lake water |
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2:30 – 2:45 |
Olav August Johannessen, University of Oxford A quantitative CDMS approach for measuring heterogeneous protein complexes |
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2:45 – 3:30 |
Coffee and Posters |
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Session 4 |
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3:30 – 4:15 |
Keynote Lecture |
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Dr Sarah Maslen (Francis Crick Institute) |
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4:15 – 4:30 |
Closing address and prizes |