Research Associate/Fellow: Developing a drug imaging workflow (Fixed term)

Vacancy Reference Number

SCI079821

Organisation:

University of Nottingham

Closing Date

10 May 2021

Salary

£27,511 to £34,804 per annum (pro rata if applicable) depending on skills and experience (minimum £30942 with relevant PhD)

Address

University of Nottingham, School of Pharmacy, Nottingham, NG7 2RD

Duration

18 months

We are seeking a Research Associate/Fellow to join a multidisciplinary project funded by EPSRC’s New Horizons Scheme.

The overall project aim is to devise a novel workflow for the imaging of drug compounds in brain tissue using complementary in vivo, in vitro and ex vivo approaches. The successful candidate will join highly motivated and well-funded research teams across the Schools of Pharmacy and Medicine. The work is a new collaboration between Rian Griffiths, Peter Harvey, Ruman Rahman and Cameron Alexander.

The aim of this post will be to devise a workflow combining complementary mass spectrometry, magnetic resonance imaging (MRI) and optical imaging approaches for monitoring of a known glioblastoma multiforme (brain cancer) drug compound. An existing drug will be tagged with a MRI active compound synthesised in a wet chemistry lab and characterised via standard synthetic techniques. This will then be used in murine models for in vivo MRI.

The successful candidate will be responsible for synthesis, utilising MRI, secondary ion mass spectrometry (ToF-SIMS) imaging and optical microscopy techniques, data processing and data interpretation. This work will be based within the Division of Advanced Materials and Healthcare Technologies, located with the School of Pharmacy and led by Dr Rian Griffiths.

The candidate will be required to undertake research and day-day management of this research project, requiring a high degree of competence in one or more of the research areas listed. An aptitude for critical thinking and a flexible approach to collaborative research is vital.

Further Information

Candidates should have a PhD thesis submitted or awarded in chemistry, biochemistry, pharmacy, or related discipline together with an interest in analytical approaches and drug delivery. This full-time (36.25 hour) post will be offered on a fixed-term contract for 18 months. Job share arrangements may be considered.

We pride ourselves on the collegial and supportive culture created by our staff. We are dedicated to creating an environment which enables both our staff to thrive and achieve their potential. Our commitment to Equality and Diversity has been recognised in the awarding of an Athena SWAN Silver Award.

Applications should be submitted via the following website: https://www.nottingham.ac.uk/jobs/currentvacancies/index.aspx

Contact Details

Informal enquiries may be addressed to Dr Rian Griffiths (rian.griffiths@nottingham.ac.uk). Please note that applications sent directly to this email address will not be accepted.