Posters
ADVANCES IN MS
61 How many scans is enough? Predicting resolving power in 2DMS experiments*
Anna Cordiner (University of York)
62 Mass spectrometry without chromatography: Analysis of mixtures by collision induced dissociation without precursor isolation
Steven Wright (Verdel Instruments)
63 Distinctive fragmentations in EI mass spectra of orthogonally protected sulphonamides and their isomeric rearrangement products
Amie Saidykhan (University of Bradford)
64 Development of helium-free direct analysis in real time mass spectrometry and application to food authenticity*
Hannah Tate (University of York)
65 SPME, ASAP-MS and Me: a sensitive and rapid approach to pesticide analysis*
Dara Lorianne Pierre (University of Surrey)
66 High throughput screening of post-translational modifications across antibody
candidates to inform machine learning*
Clare Noon (UCB)
67 Novel nano-electrospray ion source for charge detection mass spectrometry
Rob Lewis (Waters Corporation)
68 The design and characterisation of a new CDMS instrument for the analysis of megadalton-sized molecules
David Bruton (Waters Corporation)
AMBIENT & IMAGING MS
69 Optimisation of nanospray desorption electrospray ionisation (nano-DESI) probes for native ambient mass spectrometry imaging workflows
Jack Roberts (Rosalind Frankling Institution)
70 A versatile, high-throughput robotic platform for multimodal sample introduction to a SICRIT ion source
Barry Smith (University of Liverpool)
71 High-resolution microscope-mode secondary ion mass spectrometry imaging
Yuting Su (University of Oxford)
72 A novel embedding-free approach to ocular cryosection preparation for native ambient mass spectrometry*
Peter Hughes (Rosalind Franklin Institute)
73 Paper-arrow mass spectrometry for rapid cortisone analysis from salivary microsamples*
Tung-Ting Sham (University of Liverpool)
74 Rapid detection of drugs in E-cigarettes using ambient ionisation mass spectrometry*
Adam Haworth-Duff (University of Liverpool)
75 Employing EDC for semi-targeted MSI with SELECT SERIES MRT mass spectrometer and DESI XS
Ross Chawner (Waters Corporation)
76 Echo-DESI-MS for high-throughput screening of biotransformations
Rachel Smith (University of Manchester)
77 High resolution DESI imaging single cell analysis
Joanne Ballantyne (Waters Corporation)
78 Evaluation of perfused tissue for analysis of intact proteoforms by native ambient mass spectrometry (NAMS)*
Hadar Ash (University of Birmingham)
79 Evaluating ASAP-MS for rapid detection of sports prohibited substances: optimising workflows using SpectralWorks AnalyzerPro XD
Liam Heaney (Loughborough University)
BIOPHARMACEUTICALS
80 Application of high-resolution mass spectrometry workflows to characterise biopharmaceuticals and impurities
Tomas Adomavicius (Sygnature Discovery)
81 State-of-the-art mass spectrometry characterisation of adeno-associated virus (AAV)
Lauren Tomlinson (Pharmaron Biologics Ltd)
82 Improving quantitative sensitivity for peptide analysis in plasma using a novel QTOF mass spectrometer
Tom Ruane (SCIEX)
83 Proteoform specific microheterogeneity assessment of biopharmaceuticals using the Orbitrap Ascend Biopharma Edition tribrid mass spectrometer
Jonathan Bones (National Institute for Bioprocessing Research and Training)
84 Host cell protein analysis across innovator monoclonal antibody-based protein therapeutics using the Orbitrap Astral
Josh Smith (National Institute for Bioprocessing Research and Training)
85 Calibration of charge detection MS instruments
Keith Richardson (Waters Corporation)
86 Assessment of resolution and instrument type on the assessment of oligonucleotide impurities
Rachelle Black (AstraZeneca)
87 Characterisation of polysorbates in biopharmaceutical drug products using liquid chromatography mass spectrometry
Will Burkitt (UCB)
88 Top down CID MS/MS and ETD MS/MS analysis and characterisation of TryBe molecules
Sophie Lellman (UCB)
89 Ligand:antibody affinity chromatography coupled to mass spectrometry
Nisha Patel (UCB)
90 Rapid online buffer exchange with the DynaChip platform for complex native biological analysis
Suraj Dhungana (Andson Biotech)
CLINICAL & FORENSIC
91 Identification of cancer biomarkers in human breath utilising TD-GC-MS
Valerio Converso (Imperial College London)
92 Delivering real-time therapeutic drug monitoring of β-lactams using LC-MS/MS: insights from the TDM-TIME study*
Jake Lain (Manchester University NHS Foundation Trust)
93 Advancing precision medicine with mass spectrometry: The Centre for Precision Approaches to Combatting Antimicrobial Resistance
Kamila Schmidt (University of Manchester)
94 A new plasma N-glycomics-based strategy for the diagnosis of congenital disorders of glycosylation*
Alan Ribeiro Mól (Universidade de Brasília)
95 Multimodal analytical approach applied to whisky labels for authenticity determination
Veronika Tibljas (Sheffield Hallam University)
96 Identifying the amyloid fibril protein in patients with amyloid of an unknown type*
Metkel Tsegay (University College London)
97 Integrated tissue and plasma multi-omics profiling reveals distinct T2D signatures in patients undergoing CABG*
Scarlett Manley (University of Leicester)
98 Determination of the salivary steroid profile using mass spectrometry*
Mariyam Mariyam (University of Birmingham)
99 Combining DART ionization and trapped ion mobility QTOF-mass spectrometry for the analysis of controlled substances
Stephen Brookes (Bruker)
EARTH, ENVIRONMENT & FOOD
100 Understanding fluoropolymer degradation in fuel cells through mass spectrometry*
Zoe McShane (Johnson Matthey)
101 Investigation of atmospheric transfer of ‘forever chemicals’ from sewage using targeted and non-targeted HRMS*
Jishnu Pandamkulangara Kizhakkethil (Coventry University)
102 Comparison of hydrophilic-lipophilic balanced and weak anion exchange SPE for trapping airborne per/polyfluoroalkyl substances*
Amoluck Eluri (Deakin University)
103 PFAS/emerging contaminants leveraging the technique LC-VIP HESI-TIMS-HRMS and comprehensive untargeted workflows
Erik van Balderen (Bruker)
HDX & COVALENT LABELLING
104 Quantum-induced structural signalling in avian cryptochrome 4 revealed by HDX-MS
Monika Kish (University of Exeter)
105 Higher order structure characterization of ADCs using hydrogen-deuterium exchange mass spectrometry (HDX-MS)
Denis Calnan (ThermoFisher Scientific)
106 Developing traceable multi-component test materials for the validation of PFAS LC-MS methods: The EURAMET ‘ScreenFood’
Christopher McElroy (LGC Group)
ION MOBILITY MS
107 Integrating DT-IMS with compact mass spectrometry for field-deployable detection of drugs and explosives*
Mohammed Al Saud (University of Liverpool)
108 Differential mobility analyser (DMA) coupled with pixelated ion detector for illicit drug analysis in mixtures *
Cedric Boisdon (University of Liverpool)
109 Characterisation of biomolecules by ion mobility-mass spectrometry and gas phase infrared spectroscopy*
Caitlin Walton-Doyle (Freie Universität Berlin)
110 Bridging the gap between free-molecular and continuum flow regimes in ion mobility spectrometry of nanoparticles *
Kacper Kulikowski (Waters Corporation)
LIFE SCIENCES
111 When one size doesn’t fit all: LC-MS in a multi-project facility
Marina-Alexandra Machidon (University of Manchester)
METABOLOMICS & LIPIDOMICS
112 Development of an LC-MS/MS method for the combined quantification of oxysterols and bile acids*
Martin Roumain (UCLouvain)
113 Automated identification of verapamil metabolites using KNIME: comparative analysis in human, rat, and guinea pig
Nouf Alourfi (King Abdulaziz University)
114 Secondary metabolites of endophytic Hypoxylon rubiginosum isolated from Fucus vesiculosus seaweed by using spectral-based metabolomics*
Fadiah Almutairi (University of Strathclyde)
115 Using ion mobility mass spectrometry for structural characterisation of lipids to advance Parkinson’s Disease diagnostics*
Lea van Dissel (University of Manchester)
116 A novel cation-exchange chromatography-MS/MS method for metabolite and metal ion analysis in biological samples*
Rachel Williams (University of Oxford)
117 Characterisation of surfactant phospholipid synthesis and metabolism in mice models of acute lung injury*
Siona Silveira (University of Southampton)
118 A targeted LC-MS/MS lipidomics panel developed for use in clinical assays for aspirin resistance patients*
Aldred Charlesworth (University of Leicester)
119 Accelerating lipidomics: integrating microsampling devices with rapid microbore metabolic profiling (RaMMP) for UPLC-MS analysis *
Ana Sanchez Lorenzo (Imperial College London)
MS IN STRUCTURAL BIOLOGY
120 Assembly pathway of bacterial protein nanocages
Thomas Ballinger (University of Edinburgh)
121 Charge detection mass spectrometry analysis of thermally activated native protein complexes*
Anisha Haris (Waters Corporation)
122 DynaChip online buffer exchange and desalting coupled to CD-MS for the analysis of large biologics
Mason Chilmonczyk (Andson Biotech)
123 Understanding oligonucleotides: structural insights into the thrombin-binding aptamer and 38-GC using ion mobility and UVPD*
Francesca O Bellingeri (University of Leeds)
124 Adjustable source pressure regulation improves the transmission of protein complexes on Orbitrap Tribrid mass spectrometer*
Sherzod Nazarov (University of Birmingham)
125 The power of combining mutagenesis, mass spectrometry, and molecular dynamic simulations to decode nanobody stability*
Valentina Faustinelli (LGC Group)
PROTEOMICS
126 Are Solid Particles Ready for Prime-Time Proteomics?
Eduardo Shigueo Kitano (Rosalind Franklin Institute)
127 Novel recombinant chymotrypsin: a superior complementary protease to trypsin for proteomics
Jon Ditcham (University College London)
128 Standard LC-MS workflows using a single deep learning model
Shabaz Mohammed (Rosalind Franklin Institute)
129 Investigating chemical modifications of pollen proteins on exposure to air pollutants using non-targeted MS analysis *
Dimple Pathania (Deakin University)
130 Optimising mass spectrometry to study the proteoform changes in VPS35-D620N protein mutation of Parkinson’s disease
Yuko Lam (University of Dundee)
131 Ultra-sensitive quantitation and rapid method development for targeted immunopeptidomics using the Stellar Mass Spectrometer
Christopher Knowles (ThermoFisher Scientific)
132 Label-free quantitative proteomics with high precision and accuracy, driven by ultra-high-sensitivity MS/MS
Daniel Parnaby (SCIEX)
133 Keep an i-on kynurenine: proteomic profiling of WT and KMO⁻/⁻ Drosophila melanogaster via Evosep–timsTOF workflow
Muzammil Khomusi (University of Leicester)
134 Reinventing chymotrypsin: a novel recombinant analog for accurate and reliable peptide mapping of biotherapeutic proteins
Chris Moffat (Promega)
SMALL MOLECULES & PHARMACEUTICALS
135 Quantitative end-of-reaction monitoring in pharmaceutical drug development using ASAP-MS*
Catherine Welsh (AstraZeneca)
136 A high-throughput native mass spectrometry-based platform for the screening and characterisation of small-molecule drugs*
Aisha Ben-Younis (OMass Therapeutics)
137 From method to mindset: using cortisol LC-MS/MS as a structured training platform*
Paul Sampson (University of Leicester)
138 Advanced data analysis of peptide LC-MS spectra through in silico fragmentation*
Michael Sutherland (Advanced Chemistry Department UK Ltd)
139 Evaluating ethnic differences in antihypertensive drug responses in the AIM-HY cohort using LC-MS/MS analyses
Ammar Akram (University of Leicester)
140 Bridging quantification and structural resolution in lipidomics: a dual-derivatization approach based on GC-MS and LC-MS/MS*
Yicen Yue (University of Liverpool)
141 Development of a gas chromatography mass spectrometry method for urinary oestrogen profiling*
Joshua Bain (University of Birmingham)
142 Transforming quantitative sensitivity for small molecule analysis using a high-resolution workflow
Iain Mayer (SCIEX)
143 Combining high-throughput affinity selection mass spectrometry-based platform and native-MS to discover and characterize β1AR ligands
Juliana Maria De Lima (OMass Therapeutics)
144 Maximising confidence in nitrosamine analysis: strategies to prevent false positives and negatives in LC-MS
Nathanael Page (Resolian)